Hotels
United States
Saint Louis
21C Museum Hotel St Louis
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Book here and pay
10% less
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Check rooms and rates
From350US$ /night
Check-in
25Oct2025Select date
Check-out
26Oct2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
“I loved the vibrant atmosphere and proximity to Union Station!”view full review

21C Museum Hotel St Louis features contemporary art installations, a historic ambiance, and on-site dining by Idol Wolf. This 4-star Saint Louis hotel is situated in the Downtown St Louis district, offering guests a unique blend of modern amenities and artistic experiences.

Rooms & Amenities

Rooms at 21C Museum Hotel St Louis encompass a variety of accommodations, including the Luxury Double Queen and 21c King Suite, which feature modern décor, a seating area, and luxurious amenities. Most rooms come equipped with air conditioning, a safe deposit box, and flat-screen TVs with streaming services.

Dining & Culture

Dining is offered at Idol Wolf, which combines local and seasonal ingredients with traditional Spanish dishes. Guests can explore curated exhibitions and installations throughout the hotel, enhancing their culinary and cultural experience.

Recreation & Events

21C Museum Hotel includes the Locust Street Athletic and Swim Club, featuring a historic indoor pool and fitness center. The hotel also offers facilities for meetings and events, with art-filled spaces that inspire creativity.

Location & Transportation

The hotel is conveniently located within walking distance to popular attractions such as the Gateway Arch and City Museum. Public transportation options include bus stops on Olive Street, accessible within a 3-minute walk.

View all

Choose your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Corner King Room
Corner King Room
2 persons
30 m² 
1 King-size bed
Shower
Heating
room details
Deluxe King Room
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
room details
Deluxe King Suite
Deluxe King Suite
2 persons
25 m² 
1 King-size bed
Shower
Heating
room details
Corner King Suite
Corner King Suite
2 persons
44 m² 
1 King-size bed
Shower
Heating
room details
Click button to see more rooms
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Price and Room Availability

Check availability and prices for your dates now!


Getting around

Comprehensive guide to transport options for seamless travel

City Centre
Saint Louis600 m
Airports
Lambert (STL) 21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV) 40.8 km
Train
Union Station700 m
Bus
Bus stop200 m

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences
Really good Fitness Facilities
“I was thoroughly impressed with the gym at 21C Museum Hotel. It has all the equipment needed for a great workout, and I particularly enjoyed the lap pool and sauna. It made my stay feel even more luxurious!” view full review
Good Dining Experience
“I loved dining at the hotel's cafe and restaurant. The coffee was great, and the food was truly delicious! I particularly appreciated the restaurant offering diverse menu options. However, I'd recommend making a reservation in advance!” view full review
Stylish and Comfortable Rooms
“The room I stayed in was not only beautifully decorated but also spacious, providing a comfortable atmosphere. I felt truly at home with the artistic decor and the overall ambiance of the room.” view full review
Relaxing Spa Features
“I particularly enjoyed the access to the wellness facilities. The sauna was a great touch, enhancing my relaxation after a long day. The unique pool area added a refreshing element to my stay.” view full review

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
Show more

Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
City landmarks
Stadium
Busch Stadium
1.6 km
Museum
The Gateway Arch
1.9 km
Opera House
Stifel Theatre
660 m
Landmark
Old Courthouse
1.6 km
Landmark
Scott Joplin House State Historic Site
1.2 km
Stadium
Edward Jones Dome
1.4 km
Event hall
America's Center
1.4 km
Landmark
Cardinals Hall of Fame and Museum
1.6 km
Landmark
Security Building
1.3 km
Hockey Stadium
Savvis Center
850 m
Landmark
Citygarden Sculpture Park
1.2 km
Museum
National Blues Museum
1.2 km
Landmark
Kiener Plaza
620 m
Landmark
Inside the Economy Museum at the Federal Reserve Bank
1.3 km
Landmark
The Old Post Office and Custom House
910 m
Landmark
Museum of Westward Expansion
1.4 km
Fountain
Milles Fountain
620 m
Public Building
St. Louis City Hall
630 m
Landmark
Wainwright Building
1.0 km
Church
Shrine of St Joseph
1.1 km
Landmark
The Hill
820 m
Library
Central Public Library
830 m
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
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Check-in
25Oct2025Select date
Check-out
26Oct2025Select date
Rooms and Guests2 Guests, 1 Room
  • Overview
  • Rooms
  • Price calendar
  • Facilities
  • Location
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