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From143US$ /night
Check-in
09Dec2025Select date
Check-out
10Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Close to the Gateway Arch
Perfect
8.4
8.9
/10
4.2
4.2
/5

21C Museum Hotel St Louis features contemporary art installations, a historic ambiance, and on-site dining by Idol Wolf. This 4-star Saint Louis hotel is situated in the Downtown St Louis district, offering guests a unique blend of modern amenities and artistic experiences.

Rooms & Amenities

Rooms at 21C Museum Hotel St Louis encompass a variety of accommodations, including the Luxury Double Queen and 21c King Suite, which feature modern décor, a seating area, and luxurious amenities. Most rooms come equipped with air conditioning, a safe deposit box, and flat-screen TVs with streaming services.

Dining & Culture

Dining is offered at Idol Wolf, which combines local and seasonal ingredients with traditional Spanish dishes. Guests can explore curated exhibitions and installations throughout the hotel, enhancing their culinary and cultural experience.

Recreation & Events

21C Museum Hotel includes the Locust Street Athletic and Swim Club, featuring a historic indoor pool and fitness center. The hotel also offers facilities for meetings and events, with art-filled spaces that inspire creativity.

Location & Transportation

The hotel is conveniently located within walking distance to popular attractions such as the Gateway Arch and City Museum. Public transportation options include bus stops on Olive Street, accessible within a 3-minute walk.

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Choose your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
29 m² 
1 King-size bed
Shower
Heating
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Price and Room Availability

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
Explore Saint Louis
Local Highlights
Top Attractions
Activities
Dining
Entertainment
City Museum
City Museum
5 minutes walking
An interactive museum featuring repurposed architectural elements, tunnels, and artwork; fun for all ages.
Campbell House Museum
Campbell House Museum
2 minutes walking
A historic house museum showcasing 19th-century decor and art; offers guided tours of the ornate interiors.
The Gateway Arch
The Gateway Arch
25 minutes walking
The tallest arch in the world, this icon provides an observation area with stunning views of the city and river.
Scott Joplin House State Historic Site
Scott Joplin House State Historic Site
15 minutes walking
Home of the famous ragtime composer, this site offers insight into early music history; free admission days available.
Bike and Roll St. Louis
5 minutes walking
Bike rentals available for exploring the city on two wheels. Perfect for active guests and scenic rides.
Relax at Lower Meramec Park
10 minutes drive
A peaceful oasis with walking trails and picnic areas; ideal for a calming afternoon in nature.
St. Louis Market
6 minutes walking
A vibrant local market offering seasonal produce, crafts, and food; perfect for cultural immersion.
Red Oak Biscuits
Red Oak Biscuits
4 minutes walking
Casual spot with Southern-style biscuits and comfort food; breakfast favorites include homemade jam.
The Last Kitchen
The Last Kitchen
5 minutes walking
A cozy, stylish eatery serving American classics with a twist; known for innovative cocktails.
Nara Cafe and Hookah Lounge
Nara Cafe and Hookah Lounge
4 minutes walking
Offers Mediterranean dishes in a relaxed atmosphere. Ideal for late-night snacks and drinks.
Stifel Theatre
Stifel Theatre
8 minutes walking
Historic theatre hosting concerts and performances; enjoy a variety of events from comedy to music.
Kiener Plaza
Kiener Plaza
8 minutes walking
Family-friendly space often hosting outdoor concerts and festivals; a great spot for picnics and relaxation.
National Blues Museum
National Blues Museum
16 minutes walking
A tribute to the history of blues music, featuring interactive exhibits and live performances.

Getting around
City Centre
Saint Louis8 min  ·  600 m
Airports
Lambert (STL)33 min  ·  21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV)62 min  ·  40.8 km
Train
Union Station9 min  ·  700 m
Bus
Bus stop3 min  ·  200 m
Access exclusive early booking discounts.
Choose your spa escape today!
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137
FAQs
About 21C Museum Hotel St Louis
What is the distance from 21C Museum Hotel St Louis to St Louis Lambert International Airport?
The hotel is located 21 km from St Louis Lambert International Airport.
What time is check-in and check-out at 21C Museum Hotel St Louis?
Check-in is at 16:00 and check-out is by 11:00.
Is there an on-site restaurant at 21C Museum Hotel St Louis?
21C Museum Hotel St Louis features an on-site restaurant that serves Spanish cuisine.
What wellness facilities are available at 21C Museum Hotel St Louis?
The hotel offers an indoor swimming pool, a hot tub, a spa center, and fitness facilities.
What room amenities can guests expect at 21C Museum Hotel St Louis?
Rooms include air conditioning, a seating area, a flat-screen TV, a safety deposit box, and a private bathroom.
Which popular attractions are located near 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), City Museum (0.5 km), and Busch Stadium (2 km).
Is parking available at 21C Museum Hotel St Louis?
Valet parking is available for guests at the hotel.
What dining options are within walking distance of 21C Museum Hotel St Louis?
Nearby restaurants include Samwiches, Rooftop Cafe at City Museum, and Red Oak Biscuits, all located within 0.5 km.
What type of business services does 21C Museum Hotel St Louis provide?
The hotel offers a business center and meeting facilities equipped with advanced AV technology.

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Check-in
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Rooms and Guests2 Guests, 1 Room

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21C Museum Hotel St Louis Saint Louis Exterior photo

21C Museum Hotel St Louis

8.4
Great913 reviews
600 m from center
129 US$
143 US$
per night
Mobile-only price